Researchers have just lately discovered and succeeded in synthesizing conolidine, a pure compound that displays guarantee to be a powerful analgesic agent with a far more favorable basic safety profile. Even though the correct mechanism of action stays elusive, it truly is now postulated that conolidine could possibly have various biologic targets.… Read More


This compound was also tested for mu-opioid receptor exercise, and like conolidine, was uncovered to obtain no activity at the website. Making use of the exact same paw injection test, many possibilities with larger efficacy were discovered that inhibited the Preliminary ache response, indicating opiate-like action. Specified the several mechanisms… Read More


Determine five: Conolidine is antinociceptive in visceral, tonic and persistent discomfort versions and is particularly current at micromolar stages inside the brain following systemic injection.Disclaimer: The above is often a sponsored put up, the views expressed are Those people in the sponsor/author and don't stand for the stand and views of Ou… Read More